Shuai Huang

Catalytic Enantioselective Addition of Aryl, Heteroaryl, and Alkenyl Halides to Aliphatic Aldehydes

ABSTRACT Cobalt complexes of chiral Josiphos catalyzed enantioselective addition of aryl, heteroaryl, and alkenyl halides to a wide range of linear and branched aliphatic aldehydes, without using directing groups. The new method was easily scalable with low loadings of cobalt cat...