Shu G. Chen

BRD2 impedes iPSC reprogramming by regulating lipid biosynthesis and the matrisome via its ET tail

Induction of human pluripotent stem cells (hiPSCs) from somatic cells encounters significant barriers that remain poorly understood. Lipids are fundamental cellular molecules with many essential roles. However, the roles of lipids in reprogramming are unknown. Here, we show that...