Shravani Vijay Zagade

In Silico Evidence Curation and Pathogenicity Reclassification of MYOD1 Variants of Uncertain Significance in Rhabdomyosarcoma

In pediatric oncogenes, missense Variants of Uncertain Significance (VUS) pose a major challenge in clinical genetics and cancer predisposition screening. MYOD1 encodes a master basic helix-loop-helix (bHLH) transcription factor vital for myogenic differentiation, and specific al...