Shiwen Zhou

Integrated 1D‐LC‐HRMS and Heart‐Cutting 2D‐LC–MS for Impurity Profiling and Chiral Separation of Mitiglinide Drug Substance

ABSTRACT Rationale The comprehensive quality control of chiral pharmaceuticals like mitiglinide necessitates simultaneous assessment of chemical impurities and enantiomeric purity, yet conventional workflows address these separately, leading to inefficiency. This study develops a...