Shivajirao L. Gholap

Biochemical Investigation of PumG, a Key Pyridoxal 5′-Phosphate (PLP)-Dependent Aminotransferase Involved in Pseudouridimycin Biosynthesis

Abstract Pyridoxal 5′-phosphate (PLP)-dependent aminotransferases play a central role in nucleoside antibiotic biosynthesis, where they catalyze the conversion of ribose-derived aldehyde intermediates into aminonucleosides by introducing critical amino functional groups. Despite...