Shinwon Chae

Single-vesicle heterogeneity and uptake of extracellular vesicles affected by oncogenic KRAS and BRAF revealed by proteomics and nano-flow cytometry

Extracellular vesicles (EVs) facilitate intercellular communication through the transfer of bioactive molecules that modulate tumor behavior. In this study, we demonstrate that oncogenic KRAS- and BRAF-mutations alter EV composition, modify surface properties, and impact intracel...