欧阳时安(Shian Ouyang)

Clonotype-resolved T-cell response monitoring of human lung cancer TILs via repertoire-wide multidimensional TCR decoding

T cell responses across the TCR repertoire are central to immunotherapies. However, current methods cannot simultaneously achieve broad antigen coverage, high TCR resolution, and high throughput, and therefore provide only a partial view of T cell responses. Here, we introduce th...

Clonotype-resolved T-cell response monitoring via repertoire-wide multidimensional TCR decoding

T cell responses across the TCR repertoire are central to immunotherapies. However, current methods cannot simultaneously achieve broad antigen coverage, high TCR resolution, and high throughput, and therefore provide only a partial view of T cell responses. Here, we introduce th...