Shelby L. Millheim

Bacterial ribonucleoprotein bodies maintain an acidic pH environment as a mechanism of enzyme regulation

Abstract Phase separated biomolecular condensates create subcellular niches, yet their role in client regulation remains unclear. Here, we demonstrate that Bacterial Ribonucleoprotein bodies (BR-bodies) are acidic. Using ratiometric fluorescent probes in vivo , we find BR-bodies...