Shawn Zhu

Persistence of Antibiotic Resistance and Capsule in E. coli B23 after Removal from Sublethal Kanamycin Treatment

Kanamycin belongs to the aminoglycoside class of bacteriostatic antibiotics that inhibits protein synthesis. Previous studies have shown that treatment with sublethal levels of kanamycin causes the extracellular polysaccharide capsule in E. coli B23 to increase in size, and poten...

Treatment of Escherichia coli BW25113 with Subinhibitory Levels of Kanamycin Results in Antibiotic Cross-Resistance and TolC Up-regulation

To determine whether the efflux pump and outer membrane protein system, AcrAB-TolC, in Escherichia coli could be upregulated for antibiotic cross-resistance, we carried out several assays comparing cells that were primed with an initial kanamycin treatment and cells that were not...