Shaohua Zhang

β-carboline derivative Z86 alleviates pulmonary fibrosis via suppressing TGF-β/Smad signaling

Idiopathic pulmonary fibrosis (IPF) is characterized by aberrant fibroblast proliferation and excessive expression and deposition of extracellular matrix (ECM) by myofibroblasts, ultimately resulting in progressive and irreversible disorder or even loss of the pulmonary function....