Shalini Gupta

Dysregulated lncRNAs are associated with the progressive arterial phenotype in Hutchinson–Gilford Progeria Syndrome

Hutchinson–Gilford Progeria Syndrome (HGPS) is a rare premature aging disorder caused by de novo LMNA mutations. Patients develop severe systemic symptoms limiting life quality and ultimately causing death from cardiovascular events. Despite extensive research, treatment options...