Shahrzad Ashena

Association of Three HIF ‐1α Genotypes With Susceptibility and Severity of Chronic Kidney Disease

Hypoxic signaling is a critical factor in the pathogenesis of Chronic Kidney Disease (CKD). Hypoxia-Inducible Factor 1 (HIF-1) is a transcription factor that is highly expressed in the kidney and is associated with renal tubular hypoxic adaptation. Variation in the HIF-1α subunit...