Sezgin Er

A spatiotemporal cancer cell trajectory underlies glioblastoma heterogeneity

Abstract Cancer cells display highly heterogeneous and plastic states in glioblastoma, an incurable brain tumour. However, how these malignant states arise and whether they follow defined cellular trajectories across tumours is poorly understood. Here, we generated a deep single...

CADS: a comprehensive anatomical dataset and segmentation for whole-body anatomy in computed tomography

Abstract Volumetric computed tomography (CT) segmentation supports quantitative image analysis, but most AI-based methods remain organ-specific, with fragmented models, inconsistent label definitions, and heterogeneous training and evaluation protocols. Here we present CADS, a un...