Seyedeh Mahdieh Hashemi

Coumarin-triazole hybrids as potent low-toxicity anticancer agents evaluated by in vitro and in vivo 99mTc-MIBI uptake in glioblastoma models

Abstract Glioblastoma is the most aggressive primary malignant brain tumor in adults. This study examines the anticancer potential of twenty innovative coumarin-based 1,2,4-triazole derivatives, alone and in a combination with paclitaxel, against various human cancer cell lines a...