Sevinç Akçay

Mitochondrial Dysfunction across Synovial and Peripheral Compartments in Rheumatoid Arthritis: A Multi-tissue Transcriptomic Integration of PBMC, Synovial Biopsy and Whole Blood

Rheumatoid arthritis (RA) is a chronic autoimmune disease with synovial inflammation and systemic immune alterations. Mitochondrial dysfunction has been implicated in RA pathogenesis, but its tissue-specific and shared molecular signatures remain poorly characterized. We performe...