Seung Hyun Han

Dual Effects of β‐TrCP2 Deletion in Bone Homeostasis: Suppression of Osteoclastogenesis and Enhancement of Osteoblast Activity

OBJECTIVES: To elucidate role of beta-transducin repeat-containing protein 2 (β-TrCP2) in bone homeostasis for its potential as a therapeutic target for osteoporosis. METHODS: ) mice. Bone microarchitecture was assessed by micro-computed tomography, and osteoclast and osteoblast...