Seung Baek Lee

APC/C−CDH1 suppresses AROS-mediated protection against DNA damage-induced senescence by ubiquitination

Anaphase-promoting complex/cyclosome (APC/C) regulates the cell cycle by destruction of target proteins ubiquitination. However, understanding the control of APC/C has remained elusive. We identify APC2, the catalytic core subunit of APC/C, as a binding partner of active regulato...