Sergey Z. Vatsadze

Synthesis of Bispidine–Isoxazolidine-Fused Multicyclic Scaffolds via Nitrone [3+2] Cycloaddition: Toward “Hetero-Lupine Alkaloids”

Abstract We present a highly efficient strategy for the assembly of bispidine–isoxazolidine-fused multicyclic structures via [3+2] cycloaddition of alkenes to a nitrone-functionalized bispidine framework. The reaction smoothly delivers diverse hybrid heterocycles featuring comple...