Sergey Nikolaevich Avdeev

New perspectives in phenotyping and endotyping of chronic obstructive pulmonary disease

Chronic obstructive pulmonary disease (COPD) is a heterogeneous condition and a leading cause of morbidity and mortality worldwide. COPD represents a constellation of distinct etiotypes, clinical phenotypes, and pathogenetic endotypes, which necessitates a shift toward personaliz...

Chronic bronchitis in outpatient practice: unsolved diagnostic problems and therapeutic challenges

Chronic non-obstructive bronchitis (CB) represents an independent clinical condition characterized by high prevalence and a considerable contribution to respiratory morbidity, alongside a significant economic burden. Despite its seemingly benign nature, the management of patients...

Provision of biologic therapy for severe asthma and chronic obstructive pulmonary disease: an analysis of data from 51 regions of the Russian Federation

Objective. To assess the actual coverage of biologic therapy in patients with asthma and chronic obstructive pulmonary disease (COPD), the structure of its funding channels and between-region variability of provision, and to compare two independent data sources on biologic use. M...