Sergei E. Esipov

Distinguishing relapse from sustained remission in acute myeloid leukemia. Lineage-specific developmental stage distributions

We characterize bone marrow cell populations at minimal residual disease (MRD) by their distribution across hematopoietic developmental stages within each major lineage. Using the BoneMarrowMap atlas (263.159 reference cells, 24 broad cell types) as a coordinate system, we assign...