Seng Hooi John Low

Homologous Recombination Deficiency (HRD) and BRCA oncogenic variants in newly diagnosed advanced Epithelial Ovarian Cancer (EOC): first report among multi-ethnic patients

Ovarian cancer patients with homologous recombination deficiencies (HRD) exhibit specific clinical behaviours and improved responses to platinum-based chemotherapy and poly (ADP-ribose) polymerase treatment. HRD-positive patients are characterised by having genomic scar score (GS...