Sean M. Cahill

Mena EVH1 Interactswith PTP1B Via a Distributed InterfaceWithout Regulating Enzymatic Activity

Abstract The interaction between mammalian enabled protein (Mena), an actin regulatory protein, and protein tyrosine phosphatase 1B (PTP1B) is critical for maintaining epidermal growth factor receptor (EGFR) signaling homeostasis and regulating cellular motility. Mena recruits PT...