Se-Youl Chae

Engineered nanocomplex for targeted delivery of Beclin1 peptide enables autophagy-mediated tumor suppression and immune activation

Although autophagy is a central regulator of cellular homeostasis, its potential to reprogram the immunosuppressive tumor microenvironment (TME) remains largely unexplored. Within the TME, the dysregulated deposition of Tenascin-C (TNC) establishes a formidable extracellular matr...