Scott Butler

Establishment of Patient-Derived Xenotransplant and Cell Line Models for Canine B-Cell Lymphoma

High-grade canine B-cell lymphoma (cBCL) is a spontaneous cancer in dogs with similar pathologic features as human diffuse large B-cell lymphoma (DLBCL). The value of comparative oncology to both dogs and humans has long been recognized, but the progress in cBCL research has been...

Lysine iminylation derived from ω-3 polyunsaturated fatty acids

Protein posttranslational modifications (PTMs) play a central role for regulating protein function and cellular processes, with many PTMs arising from reactions with electrophilic metabolites. Here we extend the known landscape of PTMs with the identification of “lysine C 3 -imin...