Satya Narayan

CerS2-mediated lipotoxicity and calcium signaling: a novel sequential mechanism of apoptosis in cancer

Abstract The classical paradigm of the sphingolipid rheostat—balancing pro-apoptotic ceramide against pro-survival sphingosine-1-phosphate—has evolved into a complex signaling landscape where N-acyl chain length serves as the fundamental determinant of biological outcomes. This p...