Sarantis Giatrellis

Plasma membrane order maps functional diversity in immune cells

Abstract Cell membranes undergo biophysical remodeling as an adaptation to the surroundings and to perform specific biological functions. However, the extent and relevance of such changes in human immune cells remain unknown, largely because of the lack of single-cell and multidi...

Resolving cell lineages and gene functions in the developing mouse gastrointestinal tract using in utero transduction

How diverse cell lineages emerge and are genetically regulated during organogenesis are central questions in understanding the developmental origins of disease. However, the mouse gut, including its intrinsic enteric nervous system (ENS) derived from migratory neural crest, has r...