Sarah M. Bernhardt

Hepatic stellate cell activation in the postpartum liver is consistent with pre-metastatic niche establishment

Postpartum breast cancer (PPBC), diagnosed within 10 years of the last childbirth, has an increased risk of liver metastasis. In murine models, tumor transplant studies reveal that weaning-induced liver involution is a key determinant of breast cancer metastasis to the liver. Her...