Sara De Domenico

Regulation of the lncRNA NEAT1 by p53‐ ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Head and neck squamous cell carcinomas (HNSCCs) are characterized by recurrent genetic alterations, including the inactivation of the tumor suppressor TP53 gene and dysregulation of the TP63 gene. The TP63 gene encodes multiple isoforms, among which the N-terminal truncated isofo...