Sangkyu Lee

WDR23 prevents bone loss by promoting autophagic degradation of TRAF6 in osteoclastogenesis

Tumor necrosis factor receptor-associated factor 6 (TRAF6) is a pivotal adaptor molecule in the receptor activator of nuclear factor-κB (RANK) and its ligand (RANKL) signaling pathways, which are essential for osteoclastogenesis. In this study, we identified WD40 repeat-containin...