Sandra Behren

Effective Tumor Protection by a Tumor-Associated Mucin-1 Glycopeptide-Based Conjugate Vaccine in a Spontaneous Mouse Breast Cancer Model

Abstract Human mucin-1 (MUC1) is an attractive tumor antigen due to its high expression levels on tumor cells and its important roles in tumor development. Due to the aberrant glycosylation of MUC1 on tumor cells, tumor-associated MUC1 (tMUC1) has a shortened O-glycan attached on...