Sajjad Sisakhtnezhad

Sodium butyrate-mediated HDAC inhibition under hypoxic conditions modulates redox balance and tumor cell behavior in MCF-7 human breast cancer cells

Abstract Hypoxia and epigenetic dysregulation are key contributors to breast cancer progression and therapeutic resistance. However, the interaction between histone deacetylase (HDAC) inhibition and hypoxia-associated signaling remains incompletely understood. This study therefor...