Sacha A. De Serres

Association Between Donor HLA-DQ Heterodimers Group and Graft Loss in Kidney Transplant Recipients.

Background: Combinations of HLA-DQ α1 and β1 chains are restricted to specific groups: group 1 (G1), comprising DQA1*02/03/04/05/06 with DQB1*02/03/04, and group 2 (G2), comprising DQA1*01 with DQB1*05/06. A recently discovered role of HLA-DQ heterodimers in hematopoietic cell tr...