Sabiha Alam

Fmr1 mutation is associated with gut microbiome structure and diversity as well as intestinal barrier integrity and function in a sex- and genotype-dependent manner

ABSTRACT Fragile X syndrome (FXS) is the leading monogenic cause of autism spectrum disorder (ASD), caused by mutation in the Fmr1 gene. In addition to cognitive and behavioral challenges, FXS patients often experience altered gut microbiome-induced gastrointestinal (GI) problems...