Saad Ashraf

Efficacy and Safety of Baxdrostat in Hypertension: A GRADE-Assessed Systematic Review and Meta-Analysis of Randomized Controlled Trials

BACKGROUND: Baxdrostat, a selective aldosterone synthase inhibitor, has emerged as a novel therapy for uncontrolled or resistant hypertension; however, randomized controlled trials (RCTs) have shown variable results. OBJECTIVE: To evaluate the efficacy and safety of baxdrostat co...

Umbilical port versus epigastric port for gallbladder extraction in laparoscopic cholecystectomy. An updated systematic review and meta-analysis

Laparoscopic cholecystectomy (LC) is the gold standard for gallstone disease, but the optimal extraction port (umbilical vs. epigastric) remains debated. This updated systematic review and meta-analysis aimed to evaluate whether port site selection impacts perioperative and posto...

Reduced‐Port Versus Multi‐Port Laparoscopic Colectomy for Colorectal Cancer: A Systematic Review, Meta‐Analysis, and Meta‐Regression

ABSTRACT Background Reduced‐port laparoscopic colectomy (RPLC) has emerged as an alternative to multi‐port laparoscopic colectomy (MPLC) for colorectal cancer surgery, aiming to reduce operative morbidity and improve cosmetic outcomes. This systematic review and meta‐analysis eva...