S J Gu

DNMT1-targeted macrophages delivering drug-loaded nanoparticles attenuate heart allograft fibrosis via PTPRD-STAT3/6 axis

Abstract Distinct macrophage activation states play key roles in the formation and progression of heart allograft fibrosis. However, the exact molecular mechanisms that regulate the balance between inflammatory and pro-fibrotic macrophage responses during fibrosis remain poorly u...