Ryo Matsuura

Immune cell dynamics during compensatory renal hypertrophy after unilateral nephrectomy

The mechanisms underlying compensatory renal hypertrophy (CRH) in living kidney donors after unilateral nephrectomy (UNx) remain complex and underexplored. We examined immune cells involved in CRH after UNx in mice. Following UNx of the left kidney in WT mice, GFR measurements, f...

STcompare: comparative spatial transcriptomics data analysis of structurally matched tissues to characterize differentially spatially patterned genes

Abstract Motivation Comparative analysis of spatial transcriptomics (ST) data is needed to identify genes that spatially change in their expression patterns between conditions, such as in diseased versus healthy tissues. Existing methods generally fail to distinguish changes in s...