Ryan J. Sprenger

Amyloid beta plaque pathology induces chemosensory deficits and increases apnoeas in the 5XFAD mouse model of Alzheimer's disease

Abstract Sleep disordered breathing (SDB) commonly co‐presents with other ventilatory impairments in patients with Alzheimer's disease (AD). Typically reported as either obstructive (OSA) or complex sleep apnoea in AD patients, SDB results in repeated bouts of hypoxia and hyperca...