Runjin Cai

STING‑regulated Ca²⁺–TGF‑β axis drives airway remodeling and lung function decline in asthma: a multi‑omics mechanistic study

The progressive lung function decline in severe asthma is poorly explained by traditional inflammation‑centered paradigms. Calcium (Ca²⁺) dysregulation and transforming growth factor‑β (TGF‑β) signaling have been implicated, but the molecular link between them and their upstream...