Roxana Ana Covali

Deep-Learning-Based Assessment of Breast Arterial Calcification on Mammography: Technical Validation, Cardiovascular Prognostic Value, and Clinical Translation—A Narrative Review

Breast arterial calcification (BAC) is a manifestation of medial arterial calcification frequently detected incidentally on screening mammography. Increasing evidence suggests that BAC may also serve as a marker of cardiovascular risk. This narrative review critically synthesizes...

Selective Neuronal Vulnerability to Alpha-Synuclein Pathology in Parkinson’s Disease: A Critical Review of Mechanistic Rationale and Biomarker Stratification

Background: Parkinson’s disease (PD) exhibits remarkable clinical heterogeneity, with substantial variability in motor progression, cognitive decline, and the development of non-motor manifestations. Although the propagation of pathological alpha-synuclein is considered a central...