Ronan R. McCarthy

The use of Galleria mellonella to study microbial interactions, immune responses, and substrate interactions

Interbacterial interactions are diverse and complex and often dependent on the given niche these bacteria inhabit; therefore, it is often necessary to validate in vitro findings in vivo. Multiple mammalian in vivo models have been established for this purpose, from mice to larger...

Effects of cephalexin treatment on DNA replication dynamics in Escherichia coli

Abstract Background In bacteria, DNA replication and chromosome segregation are tightly coordinated with cell division. The replication run-out method, which combines inhibition of transcription initiation by rifampicin with inhibition of cell division by cephalexin, is widely us...