Romano V. A. Orrù

One-Pot Aqueous Assembly of Sulfimides from Thiols, Alkyl Halides, and Oxaziridines

A sequential one-pot method for the aqueous synthesis of sulfimides from thiols, alkyl halides, and an oxaziridine nitrogen-transfer reagent is reported. Thiols are first S-alkylated under aqueous conditions, and the resulting sulfides are converted directly into sulfimides witho...