Roland Jahns

Heart-reactive antibody levels differentially associate with ventricular function in hereditary cardiomyopathies

Abstract Background gCMP are a major cause of cardiovascular morbidity and mortality. While agonistic anti-β1-adrenergic receptor antibodies (anti-β1AR-EC II ) have a recognized pathogenic role in idiopathic dilated cardiomyopathy (DCM), the relevance of HRA in gCMP remains uncle...

Cytomegalovirus Latency Fuels Inflammation Following Myocardial Infarction

BACKGROUND: Epidemiological studies have consistently associated cytomegalovirus (CMV) seropositivity with adverse cardiovascular outcomes. However, the mechanisms by which cytomegalovirus infection impacts pathophysiology in the heart remain poorly understood. In this study, we...