Rogério Aparecido Bataglioli

Prophage-encoding engineered bacteria enable prophylactic lytic phage therapy for enteric infection in mice

Phage therapy is a promising antibacterial approach but it has limited efficacy against enteric bacterial infections, such as Salmonella enterica Typhimurium (STm). Here we hypothesized that establishing high concentrations of a pathogen-targeting phage in the gut before infectio...