Robert Figlin

Mitochondria-targeted DZ-1-dihydroartemisinin conjugate induces Bax/Bak-independent apoptotic cell death in colorectal carcinoma cells

Artemisinin and its derivatives possess anti-malarial as well as anti-cancer properties against various malignancies. However, their clinical application as anti-cancer agents is limited by several factors, most notably a lack of tumor selectivity. To address this limitation, we...