Riley E. Stein

Deciphering Interheme Electron-Transfer Pathways in a Diheme Peroxidase from Methane-Oxidizing Bacteria

Abstract Bis-FeIV-forming enzymes represent an emerging paradigm in high-valent heme iron chemistry, in which two hemes separated by 15–20 Å are both oxidized to the FeIV state. A tryptophan positioned between the two hemes in two out of the three known enzymes to form this state...

Identifying the proton donor in electrocatalytic hydrogen evolution by a model hydrogenase

Abstract Proton transfer is essential in all multi-electron transformations. Identifying the proton donor in such processes is crucial to understanding the catalytic mechanism and optimizing activity through pK a matching, which can enhance proton transfer rates. However, aqueous...