Ri-Sheng Chen

CAMM-Based Rational Hapten Design for Monoclonal Antibodies with Different Specificities against Avermectins and a Sensitive Chemiluminescence Immunoassay

Abstract Computer-aided molecular modeling (CAMM) has become an important tool for guiding rational hapten design. Avermectins are a family of macrocyclic lactones with highly similar structures, making monoclonal antibody (mAb) specificity difficult to control. In this work, we...