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Sequential Dual Catalysis Merging Enantioselective Cu-Catalyzed Conjugate Addition with Intramolecular Pd/Ir-Catalyzed Allylic Alkylation

The combination of asymmetric conjugate addition and allylic alkylation has emerged as a powerful strategy for the stereocontrolled construction of complex molecules. However, such transformations have been largely limited to intermolecular processes and have not been explored on...