René Pool

APOE ε4 carriership status enhances age-related changes in Alzheimer’s disease plasma biomarkers concentrations

Alzheimer’s disease (AD) plasma biomarkers are cost-effective tools to detect early stage amyloid pathology. We investigated how interactions between AD genetic risk (apolipoprotein E (APOE) ε4, AD polygenic risk score (excluding APOE; PRSAD)), age, and sex affected AD plasma bio...