Rebecca L. Melen

Catalytic Stereoselective Intermolecular Fluoroacylation of Unactivated Alkynes via C–F Bond Reconstruction

Abstract Herein, we report a transition metal-free synthesis of monofluoroalkenes via a C–F bond reconstruction approach. The process employs inexpensive BF3·Et2O as a catalyst for the stereoselective intermolecular fluoroacylation of unactivated alkynes with alkyl/aryl acid fluo...