Ravi Prakash Singh

Enantioselective Pericyclization of Naphthol-Substituted Alkynyl Ketimines

Abstract A vinylidene ortho-quinone methide (VQM)-mediated, organocatalyzed tandem 6π-azaelectrocyclization and dearomatizing spirocycloaddition of naphthol-substituted alkynyl ketimines, facilitated by NBS, have been realized. This strategy enables the enantioselective synthesis...

Asymmetric Access to Spirobenzofuran Oxindoles via Organocascade Reaction of Unprotected 3-Chlorooxindoles with 2-Hydroxy-β-Nitrostyrenes

Abstract A highly enantioselective methodology has been developed to access oxindole-fused spiro dihydrobenzofuran, applicable to a protecting-group-free reactant, with high bond efficiency (1 new C–C and 1 C–O bond) and two contiguous stereocenters. Gram-scale and stereodivergen...